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From a PK point of view, no dose adjustment of semaglutide was shown to be required for different populations based on sex, age, race, ethnicity, or renal function

Always read labels, take as directed, and consult a healthcare professional as needed

Signs you may need a dose adjustment Contact your healthcare provider if you notice any of the following: Persistent mood changes or low energy after several weeks Ongoing side effects like insomnia, nausea, or restlessness Little or no change in appetite or weight despite consistent use (when using for off-label weight loss)

Even with manufacturer savings cards, most people pay hundreds per month for the brand-name versions