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Conversely, a portion of uric acid is secreted back into the proximal tubular lumen through various apical transporters, including ABCG2, NPT1, NPT4, and GLUT9, along with the basolateral transporters OAT1 and OAT3

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[7] This is why the two are frequently studied as complementary rather than competing mechanisms: the entire rationale for the CagriSema combination is that pairing an amylin analog (cagrilintide) with a GLP-1 analog (semaglutide) engages two different hormone systems together

A common alternative is chylomicrons, lipoproteins consisting of a mixture of proteins and fatty substances