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Data Analysis We compared the events of interest in patients randomized to use of GLP-1 agonists versus the events in patients randomized to the control strategy (placebo or other antihyperglycemic medications)

A number of mechanisms have been proposed to underlie the proatherogenic properties of sdLDL, including increased susceptibility of oxidation (464) and glycation (465), promoting arterial retention and increased macrophage foam cell formation

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However, due to technical limitations in measuring glucagon secretion in zebrafish 16 , we were unable to determine whether GCGR deficiency increases glucagon secretion at the single-cell level