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Diabetes Care 23:295301 Vukovich MD, Costill DL, Fink WJ (1994) Carnitine supplementation: effect on muscle carnitine and glycogen content during exercise

It is due to the inactivation of the glutathione (GSH)-dependent antioxidant defense mechanism in cells, and the ability of GPX4 to suppress lipid ROS accumulation is inhibited, which eventually leads to lipid peroxidation and cell death ( Three factors are closely related to ferroptosis: iron, polyunsaturated fatty acids, and amino acids

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Sin embargo, es esencial ser consciente de estos posibles efectos secundarios para controlarlos de forma eficaz