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Myotonic dystrophy type 1 is associated with nuclear foci of mutant RNA, sequestration of muscleblind proteins and deregulated alternative splicing in neurons

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Women who are willing to avoid pregnancy for at least 612 months after Radioiodine therapy Patients with increased surgical risk (comorbidities, prior neck surgery or neck radiation) Lack of access to high-volume thyroid surgeon Reasons not to use radioactive iodine include: Moderate to severe thyroid eye disease due to the risk of worsening eye disease

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