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RAGE binds preamyloid IAPP intermediates and mediates pancreatic beta cell proteotoxicity

identified five essential differentially expressed ferroptosis-related genes (NOX1, ACVR1B, PHF21A, FTL, and GALNT14) that may be related to the pathogenesis of PCOS, providing a new perspective for the clinical diagnosis and treatment of PCOS (169)

In addition, rather than leading to an increase in rT3 levels directly caused by an imbalance in DIO3, the available data imply that Se deficit may indirectly cause these levels to rise via reduced clearance of DIO1 and changes in peripheral thyroid hormone metabolism [33]