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Further, transport of infliximab was reduced in the presence of IgG1-REW, supporting a competitive advantage for the Fc-engineered antibody (Fig

Activation of the Nrf2/ARE pathway can mitigate these effects by enhancing the bodys antioxidant capacity and reducing inflammation

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For instance, extracts from Guizhi Fuling Pills and Paeonia bark gum (Baikejiao) have been reported to downregulate transferrin receptor 1 (TfR1) and upregulate ferroportin 1 (FPN1) expression, thereby facilitating the restoration of intracellular and extracellular iron equilibrium (Liu R