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Structuring for Uncertainty But fast scale-up requires creative deal structures as acquirers navigate uncertainty over drug demand, development timelines and divergent regulatory regimes at a time of heightened geopolitical tensions

depending on the distance from the tumor site, TRMs tend to increase in number with proximity, and TRMs can promote or inhibit the progression of different tumor types, exhibiting spatial heterogeneity (242)

Therapeutic potential: Provides a model to study mechanisms that could inform future obesity and metabolic disorder interventions