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Advances in spatial multiomics and single-cell transcriptomic techniques, along with insights into aberrant signaling via myokines, cytokines, hormones, the gut microbiota, and exosomes, have revealed the molecular heterogeneity and dynamic inter-organ crosstalk underlying diabetes

Identification of a mutation that relieves gamma-glutamyl kinase from allosteric feedback inhibition by proline

GLP-1 medications are FDA-approved with extensive clinical trial data

Reduction of metabolic syndrome: Researchers are exploring its role in creating a substantial relief and improvement of broader metabolic parameters (such as metabolic rate), including nutrient metabolism, lipid profiles, insulin resistance, glucose homeostasis, appetite control, and visceral adiposity