Further embodiments include a thermoreversible gel in the otic pharmaceutical formulation, such that upon preparation of the gel at room temperature or below, the formulation is a fluid, but upon application of the gel into or near the auris interna and/or auris media target site, including the tympanic cavity, round window membrane, or the crista fenestrae cochleae, the otic-pharmaceutical formulation stiffens or hardens into a gel-like substance
M., Cuenca-Acebedo, R., Luque de Castro, M
It is not a drug, dietary supplement, or product intended for human or animal consumption.
Handling quality preserves activity but has no bearing on the absence of blend-level efficacy data