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Treatment with GABA significantly restores neuron density compared to the model group, as evidenced by the large improvement and the ( p = 0.002), underscoring its neuroprotective effects
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Nevertheless, the imbalance of redox activity is a crucial step in DILI as most hepatotoxic drugs determine a build-up of ROS and induce oxidative stress by different mechanisms such as an increase in intracellular oxidants and depletion of antioxidants that finally lead to mitochondrial dysfunction [60,61]
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