Hyponatraemia (low sodium) is common in cirrhosis due to fluid retention, dilution, and neurohormonal changes
In the randomized placebo-controlled HOME trial of 390 adults with type 2 diabetes (de Jager and colleagues, Long term treatment with metformin in patients with type 2 diabetes and risk of vitamin B-12 deficiency, BMJ, 2010), metformin lowered serum B12 by a mean of 19 percent over 4.3 years
Abdrabou Abouelmagd A, Abdelrehim AM, Bashir MN, Abdelsalam F, Marey A, Tanas Y, Abuklish DM, Belal MM
20,21 Personal device monitoring Prospective studies of environmental exposures may use personal device monitoring which allows for personalized assessment of chemical exposures over a period of time