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When these muscles weaken, the spine may temporarily experience: increased disc pressure reduced spinal stability greater strain on spinal joints increased risk of disc irritation This can sometimes lead to symptoms such as: lower back pain neck stiffness nerve irritation sciatica Do Ozempic and GLP-1 Drugs Cause Muscle Loss

Key Considerations for Patients on Ozempic or Mounjaro Current NHS Guidance The current Prescribing Guidelines Document (PGD) for most NHS hospitals do not list contraindications or cautions regarding the combined use of corticosteroids with Ozempic or Tirzepatide

The side effects noted above can lead many people to stop taking the medications, according to JAMA Network or, because they are losing weightto stop exercising, which can lead to muscle loss

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