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In contrast, a balanced and diverse gut microbiome supports brain health by reinforcing intestinal barrier function, regulating peripheral and central immune responses, and synthesizing neuroactive compounds such as SCFAs, tryptophan metabolites (Savonjie and Weaver, 2023), and gamma-aminobutyric acid (GABA)
FIGURE 9 Summary and conclusions: Glutathione and early (premature) inflammaging Chronic inflammatory diseases especially those compromising the lower respiratory system (chronic obstructive pulmonary disease, lower respiratory infections, cystic fibrosis, idiopathic pulmonary fibrosis, acute respiratory distress syndrome), diseases compromising the cardiovascular system (atherosclerosis, ischemic heart disease, stroke, and others), many other systemic inflammatory diseases like diabetes (274, 275)