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The honest answer is that the mechanism is well established, the preclinical evidence is genuinely encouraging, and the human clinical evidence is still developing

Quantification of residual pyrrolidine by GC-FID To further validate the removal of pyrrolidine by this process, a study was performed using gas chromatography with flame ionization detection (GC-FID) to quantify the amount of residual pyrrolidine after completing a deprotection step, draining the mixture, and adding fresh DMF to the reaction vessel

[11] For paracetamol overdose, it works by increasing the level of glutathione, an antioxidant that can neutralize the toxic breakdown products of paracetamol