Ultra-performance liquid chromatography-tandem mass spectrometry (UPLCMS/MS) UPLCMS/MS performed on a Waters Acquity UPLC-Xevo TQ-S UPLCMS/MS system equipped with an Acquity BEH HILIC (2.1 100 mm, 1.7 m) chromatographic column was employed to determine TMA, TMAO, choline, betaine, -butyrobetaine, betaine aldehyde, butyryl-carnitine, isovaleryl-carnitine, OH-isovaleryl-carnitine, stearoyl-carnitine, oleoyl-carnitine, linoleoyl-carnitine, myristoyl-carnitine, lauroyl-carnitine, and decanoyl-carnitine as described previously 31,41
References Ademoyero, Adedamola A., and Pat B
In health, postprandial glucose elevation triggers pancreatic beta-cell insulin secretion in a biphasic pattern, facilitating glucose uptake in skeletal muscle, adipose tissue, and hepatic suppression of gluconeogenesis
Pridgeon JW, Olzmann JA, Chin L-S, Li L