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This review provides an initial guide for clinical practice and patient education for optimizing nutrient status, preserving lean mass and muscle strength, supporting metabolic health, and reducing gastrointestinal side effects

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Researchers from Sun Yat-sen Univeristy uncover that lactate-induced #lactylation of the #helicase BLM at Lys24 enhances #HomologousRecombination repair and drives #anthracycline resistance, while #irinotecan counteracts this by suppressing BLM lactylation, offering a promising strategy to overcome #chemoresistance in #cancer