The intestinal epithelium functions as a selectively permeable interface, enabling the transcellular and paracellular transport of key nutrients, electrolytes, and water, while simultaneously restricting the entry of potentially harmful substances such as food antigens, digestive enzymes, endotoxins, pathogenic microorganisms, and their associated toxins
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In spite of this, if you search for "hyaluronic acid vs sodium hyaluronate" you will find on multiple places that sodium hyaluronate is smaller and can penetrate the skin better
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