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After being phosphorylated, IRS-1 and IRS-2 attach to and activate proteins that contain the Src homology-2 (SH2) domain, including phosphoinositide 3-kinase (PI3K)

Athletes subject to anti-doping controls remain responsible for these substances at all times

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Studies also suggest that it may eventually be developed into an orally available and safe therapeutic agent for obesity, making it a convenient option for patients [2]