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Representation of Asian participants has been somewhat less consistent, with some years showing spikes by some NIH institutes/centers (mostly driven by a 2017 increase in Asian recruitment by trials supported by the National Cancer Institute)
Patients and prescribers should exercise caution and seek professional advice, considering the individual's health profile, potential drug interactions, and pre-existing conditions
realizing its full clinical potential will likely depend on rationally designed combination strategies that simultaneously target complementary resistance pathways and leverage ferroptosis as a cornerstone of precision oncology for colorectal cancer
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