Numerous collaborative initiatives with the final aim of drug repurposing were objects of debate, among wich: The AZ Open Innovation program, the NIH National Center for Advancing Translational Sciences (NCATS) program: Discovering New Therapeutic Uses for Existing Molecules, the Medical Research Council (MRC) and AstraZeneca (AZ) Mechanisms of Human Disease Initiative, The Clinical and Translational Science Award (CTSA) Pharmaceutical Assets Portal, European College of Neuropsychopharmacology (ECNP) Medicines Chest Program, Pfizers SpringWorks Program, the AstraZeneca/National Research Program for Biopharmaceuticals (NRPB) partnership in Taiwan, the Roche/Broad Institute Collaboration, and the Drugs for Neglected Diseases Initiative (DNDI), the Clinical Development Partnerships Initiative (Krishnamurthy et al., 2022)
During this phase, injection frequency is higher to build systemic levels of the peptide and begin the actin regulation and angiogenesis responses
Allium sativum , a potential phytopharmacological source of natural medicine for better health
Although we narrowed down our inclusion criteria to only accept reports published in English, which may have improved quality, studies with optimistic results were still more favored for publication than those with negative findings