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According to current evidence and the Summary of Product Characteristics (SmPC) approved by the Medicines and Healthcare products Regulatory Agency (MHRA), there is no established direct pharmacological mechanism by which Ozempic alters potassium homeostasis

These risks have led to a wave of lawsuits against the manufacturer, Novo Nordisk, with claims that the company failed to provide adequate warnings about these potential dangers

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The beneficial effect of caffeine in reducing memory impairment by regulating the expression of brain-derived neurotrophic factor (BDNF) and tropomyosin receptor kinase B (TrkB) or by regulating the expression of nuclear erythroid 2-related factor (Nrf2) and Toll-like receptor 4 (TLR 4)-induced glial cells-mediated neuronal cell death and neuroinflammation [46]