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[30] [31] The EFSA also considered the maximum safe intake and like the US National Academy of Medicine, decided that there was not sufficient information to set an UL

Oxidative stress is characterized by excess reactive oxygen species that overwhelm endogenous antioxidant defenses and significantly contribute to endothelial dysfunction in ED [9]

Moreover, oxidative stress can enhance the expression of adhesion molecules and proteases, facilitating cancer cell detachment, invasion into surrounding tissues, and entry into the bloodstream [120]