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In addition, alcohol reduces the levels of naturally occurring antioxidants in the body resulting in an excess of oxidative stress, which further extends its harmful effects

Another study, SPaT, found that non-dysplastic patients with a high-risk TissueCypher score progressed to cancer more often than Barretts esophagus patients with low-grade dysplasia, with an annual cancer progression risk of 6.9% (1 in 14) (Frei et al., 2020)

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