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AE: Data curation, Formal Analysis, Investigation, Methodology, Validation, Visualization, Writing review & editing

Per the program's published design paper (Giblin et al., Diabetes, Obesity and Metabolism , 2026), the core registrational program consists of four trials : TRIUMPH-1 (NCT05929066): 80-week weight management basket trial, adults with obesity/overweight without diabetes (N=2,339), with knee osteoarthritis and obstructive sleep apnea substudies nested inside it

It copies a natural gut hormone your body releases after eating

And they improve immune signaling from adipose tissue and the gut, two sites intimately connected to autoimmune thyroid disease progression