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Tirzepatide is a dual GIP and GLP-1 receptor agonist approved by the FDA for type 2 diabetes management (Mounjaro) and chronic weight management (Zepbound) in adults with obesity or overweight with weight-related comorbidities

Moreover, BAs have been reported to modulate appetite by directly binding with their receptors in the gastrointestinal tract to regulate the secretion of appetite-associated hormones

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