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Novo's February 2026 announcement of a 50 percent Wegovy list price cut (to $675, effective January 2027) suggests the company is already moving in this direction, though $675 remains well above MFN levels

The published human evidence is thin and does not yet confirm it: in a small controlled study of healthy elderly men with low baseline IGF-1, six weeks of nightly GHRH injections increased nocturnal growth hormone release and improved two of six muscle-strength measures, but produced no measurable change in weight, waist-to-hip ratio, or DEXA-assessed fat and muscle mass (7)