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Such product candidates are not approved by the CONTACT: References 1 These reported efficacy data are based on a standard analytical measure commonly used for obesity medicines, the efficacy estimand, per Amgens investor presentation on November 26, 2024

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Alanine aminotransferase (ALT) levels, which indicate liver cell injury, declined substantially in patients achieving 10% or greater weight reduction

Patients with complicated medical histories, kidney disease, or ongoing psychiatric medication management may benefit from hybrid carecombining telehealth convenience with periodic in-person evaluation from their primary care team