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While these variants contribute to GI sensitivity, they don't definitively predict diarrheadiet, hydration, and gut bacteria also matter significantly

Follow the dosage escalation below to reduce the risk of gastrointestinal adverse reactions [see Warnings and Precautions (5.6 ) and Adverse Reactions (6.1 )]

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Symptoms accompanied by excessive thirst, decreased urine output, or dry mucous membranes point toward dehydration