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In the second arm, the team compared more than 32,000 GLP-1 patients against more than 96,000 patients taking SGLT-2 inhibitors between 2013 and 2020

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Therapeutic potential of semaglutide, a newer GLP-1 receptor agonist, in abating obesity, non-alcoholic steatohepatitis and neurodegenerative diseases: A narrative review

Beyond homeostatic regulation, current evidence also supports the role of GLP-1 in hedonic feeding, which is driven by palatability rather than physiological need [52], and involves neurobiological pathways related to mesolimbic dopamine transmission and mechanisms related to reward processing [53]