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The GLP-1 semaglutide (#Ozempic) failed to improve mood and executive functioning in this, the first RCT of a GLP-1 for major #depression: sciencedirect.com/science/articl Weight loss was significant (all subjects were overweight/obese)

The company is marketing the product as a cheaper alternative to the pair of drugs, which are currently in short supply

The FDA has issued specific warnings about compounded semaglutide products, particularly those using semaglutide sodium salt, which may contain impurities, incorrect dosages, or entirely different substances than labeled

Advocacy groups and grieving parents continue to call for stronger safeguards to prevent what they describe as a digital drug market targeting young users