Urate, also known as uric acid, is a major endogenous antioxidant that is neuroprotective against both astrocyte-induced toxicity in SOD1 G93A mice and H 2 O 2 induced oxidative stress in cells expressing mutant SOD1 G93A (Bakshi et al., G85R cellular and Drosophila models (Zhang et al., 2019b)
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A similar conversation is now emerging around obesity medicines: GLP-1 and dual agonists are being recognised internationally as evidence-based treatments for obesity with cardiometabolic benefit.[8] Indian insurers may progressively consider coverage when obesity is severe and linked with diabetes, heart disease, or sleep apnoea, rather than for cosmetic weight loss alone.[10] For families, this could mean negotiating group policies and reading the policy wording carefully to see if medically supervised GLP-1 therapy for obesity-with-complications is covered