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In colorectal cancer models, the combination of CB-839 and cetuximab significantly inhibited cell proliferation and increased apoptosis and necrosis, accompanied by decreased levels of the mTOR signaling target pS6, resulting in delayed tumor growth

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Following light irradiation assays, the illumination efficacy was assessed in comparison with the dark control by plating serial dilutions of each sample on Brucella agar plates with 10% FBS as described previously ( Scanning Electron Microscopy In order to examine the effects of irradiation at 405 nm on bacterial surface morphology, non-irradiated and irradiated samples were observed by scanning electron microscopy

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Endocrinology 154 , 35773588 (2013)

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