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Circumvention of normal constraints on granule protein gene expression in peripheral blood neutrophils and monocytes of patients with antineutrophil cytoplasmic autoantibody-associated glomerulonephritis

Yadav B, Chauhan M, Shekhar S, Kumar A, Mehata AK, Nayak AK, Dutt R, Garg V, Kailashiya V, Muthu MS

66 It also inhibits the activation of nuclear factor erythroid 2-related factor 2 (NRF2), exacerbating oxidative stress injury to the kidneys

In developed countries, excessive calorie intake and frequent consumption of unhealthy foods, associated with a sedentary lifestyle, have caused an increase in the prevalence of obesity, which in turn predisposes to several non-communicable diseases, such as cardiovascular disease, diabetes, hypertension, and chronic kidney disease [9]