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Liver disease is often called silent because so many patients don't feel any symptoms and their illness goes undiagnosed, but it is the ninth leading cause of death in the U.S

Specifically, under normal conditions, the eukaryotic initiation factor-2 (eIF2) complex (composed of alpha, beta, and gamma subunits) assists with RNA translation via ribosomal recognition of the AUG start codon [227]