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Next, we treated HepG2 cells with BCNU, a chemical inhibitor of GR, the enzyme converting GSSG back into GSH

In addition, melatonin inhibits ferroptosis and renal tubule dilation to improve renal injury in the CLP/LPS-induced AKI mice model by activating SIRT3 and up-regulating the Nrf2/HO-1 pathway to inhibit ferroptosis induced by SAKI (Qiu et al., 2022)

Crossref Winter JA, Letley DP, Cook KW, et al

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