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para-Nitrophenylphosphate
and specificity of promoters using lacZ as a reporter
D-Tryptophan
ultimately inhibiting protein synthesis
Rifaximin W270 para-NitrophenylphosphateRifaximin is used to inhibit susceptible Gram positive and Gram negative bacteria and to investigate transcriptional inhibition and rifamycin resistance mechanisms. It is incorporated into culture media to apply selective pressure in strains carrying rifamycin resistance determinants or to evaluate mutations affecting bacterial RNA polymerase. Rifaximin is a semisynthetic rifamycin derivative with minimal aqueous solubility and limited diffusion in
