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Gefitinib N125 β-Nap-β-D-Gal

SKU: 29956140445

4.4
USD68.00 USD105.00

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Ships within 48 hours · Estimated delivery Aug 10 - Aug 15

Description

β-Nap-β-D-Gal

In pancreatic islets

clear solution when dissolved 1% in water

Fusaric acid

Gefitinib N125 β-Nap-β-D-GalGefitinib is an anti cancer agent similar to erlotinib. It functions through inhibiting the overexpressed or mutated epidermal growth factor receptor (EGFR) by binding its ATP binding site. Overexpression and mutation of EGFR are common in cancer cell lines and may lead to uncontrolled proliferation through the Ras signaling cascade. Gefitinib has been shown to induce tumor cell apoptosis in HaCaT cells, KG 1 cells, P39 cells, and CD34+ myeloblasts.

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