many different animal species are studied in the laboratory, including terrestrial (land), aquatic (water), and microscopic animals Antioxidant - a compound that prevents or repairs the damage caused by reactive oxygen species Arterial calcification - an active, organized, highly complex process, similar to normal bone formation, in which calcium salts are deposited at sites of atherosclerotic plaque rupture Artery (adjective: arterial) - a muscular-walled blood vessel that carries blood away from the heart Calcification - the deposition of calcium salts in tissues Lipoprotein - a sphere-like particle that carries cholesterol and triglycerides through the bloodstream Observational study - a human research study in which no experimental intervention or treatment is applied, and participants are simply observed over time Oxidative stress - a situation in which the production of reactive oxygen species exceeds the ability of an organism to eliminate or neutralize them Plaque - a deposit of fat, cholesterol, immune cells, fibrin (a blood clotting protein), and other substances that forms inside arterial walls Randomized controlled trial - a human research study in which participants are assigned by chance alone to receive either an experimental agent (the treatment group) or a placebo (the control group) Reactive oxygen species (ROS) - highly unstable oxygen-containing compounds that react easily with nearby cellular structures, potentially causing damage Test tube - a research experiment performed in a test tube, culture dish, or other artificial environment outside of a living organism
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The distinction among tolerance, dependence, and addiction is explained in detail below
