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According to the International Classification of Diseases (ICD-11) published by the World Health Organization (WHO), diagnosis code 6C4A.2 is defined as a disease called nicotine dependence, and according to the manual of diagnosis and statistics of mental disorders (DSM-5) published by the American Psychiatric Association (APA), tobacco use disorder is classified as a disease belonging to addiction disorders

The irritation effect, on the other hand, is the lingering harsh sensory property of smoke

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