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In line with prior evidence on the price elasticity of tobacco productsindicating that smokers are more likely to quit as prices increase, especially among young adults and individuals with low socio-economic status 504 we observed significant positive effects of tax/price increases on quit rates, quit attempts and quit intentions and significant negative effects on cigarette consumption and smoking prevalence

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All 33 randomized subjects were included in the safety, PK and the OPL analysis populations for both primary and secondary endpoint measurements