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[8] Nonetheless, treatment with cotinine in humans was reported to have no significant physiologic, subjective, or performance effects in one study, [9] though others suggest that this may not be the case

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HPLC and mass spectrometry were carried out following previous methods, with modifications ( Monoamine oxidase A activity, qRT-pCR and dopamine content ELISA kit The striatum of mice was excised with a mold in a buffer solution at 4C, quickly frozen in liquid nitrogen, and stored at 80C