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(a) Smoking and mutation Each puff of a cigarette contains several carcinogens belonging to multiple chemical categories such as PAHs, TSNAs, aromatic amines, metals, oxidants and free radicals that cause genotoxicity leading to eventual development of invasive cancers from healthy normal tissues [24]

On the one hand, advocates of e-cigarettes stress their potential as a smoking cessation tool, citing studies suggesting that they can help smokers reduce or stop their tobacco consumption

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Nicotine is an addictive chemical, and evidence suggests that nicotine use during adolescence and young adulthood has long-term impacts on brain development