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Carlsson and colleagues hypothesised that the effect of nicotine could explain these findings, with experimental studies previously linking nicotine to impaired insulin sensitivity

Observational studies have identified associations between tobacco useincluding smokeless formsand increased risk of developing fatty liver disease

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Heres how smoking harms liver health in multiple ways: Increased Risk of Liver Diseases: Tobacco use is associated with a higher risk of developing non-alcoholic fatty liver disease (NAFLD), non-alcoholic steatohepatitis (NASH), and hepatocellular carcinoma (HCC)the most common type of liver cancer