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If you arent used to taking nicotine, you might feel: Dizziness Headache Racing heart Nausea / possible vomiting Stomach cramps Weakness People who use nicotine regularly build up a tolerance to the immediate short-term effects so after a while you might feel: Mild stimulation Increased ability to concentrate Relaxation Temporary reduction in the urge to smoke (or to vape) / not wanting to smoke as often How long it takes for nicotine to kick in and the time its effects last depend on how you take it

Nicotine withdrawal can temporarily worsen symptoms of depression, anxiety, and irritability