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Eligible studies investigated the effects of tobacco exposure on microbial composition and its association with local or systemic pathophysiological outcomes, including inflammatory, metabolic, and neoplastic processes

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Currently, there 17 states in the U.S

So selling IQOS in the US isnt going to solve the problem. The FDA approval could change the cigarette market in the US but it wont solve the smoking problem If the US joins the club of 29 countries where IQOS is already being sold, it could mean a sea change in the status quo around smoking in this country: IQOS would be the first FDA-approved tobacco product thats allowed to be marketed to Americans as safer than cigarettes