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As per previous UKB studies [14], participants were excluded if they reported any of the following neurological conditions/incidents: dementia, Parkinsons disease, brain cancer, brain hemorrhage, brain abscess, aneurysm, cerebral palsy, encephalitis, head injury, nervous system infection, head or neurological injury, trauma, stroke, or other chronic degenerative neurological problem (including demyelinating diseases)

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Other cigarette design features have not been considered to date in non-industry research of the risks of filtered and non-filtered cigarettes because the product features themselves were considered propriety information by manufacturers and were shared neither with members of the research community nor the public