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Tobacco use has been strongly linked to several major types of heart disease, including: Smoking and heart disease Early Symptoms of Heart Disease from Smoking Heart disease often develops silently, but watch for these early warning signsespecially if you smoke or use tobacco: Shortness of breath, even with light activity Chest pain or pressure (angina) Fatigue or weakness without clear cause Irregular heartbeat or palpitations Swelling in legs or ankles Dizziness or fainting If you notice any of these symptoms of heart disease, speak to your cardiologist promptly