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We enrolled only occasional smokers with low cumulative cigarettes pack-year in this study, instead of never-smokers, because we believed that the latter would not be able to vape e-cigarettes as required in this protocol

This order keeps the decision practical and reduces the chance of buying the wrong format

One recent study, for example, found that children as young as 12 who had smaller orbitofrontal cortices were significantly more likely to start smoking weed by the time they were 16 a hint that the brain differences came first

Fittingly, for our video call, Gonzalez opts not to turn his camera on, so Im interviewing a black screen