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Nearly all modern chewing tobaccos are produced by leaf curing, cutting, fermentation, and processing, which may include sweetening and flavoring

These products contain nicotine -- either synthetic or extracted from tobacco -- but not tobacco

Smoking generates harmful chemicals, which can cause lung issues

Second, if multiple risk estimates with different adjustment levels were reported in a given study, we included only the fully adjusted risk estimate and modeled the adjustment level according to the number of covariates adjusted for (rather than which covariates were adjusted for) and whether a standard adjustment for age and sex had been applied